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Home / Primary Antibodies

Gastrin Antibody (V7861SAF)

SKU : BHA17127006

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NSJ Bioreagents

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Mfr.No.	V7861SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in tu, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A recombinant full-length human GAST protein was used as the immunogen for this Gastrin antibody.
Isotype	Mouse IgG2c, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P01350

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Gastrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA
Description	ELISA (order BSA-free format for coating)

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/gastrin-antibody-gast-2631-v7861" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127006	V7861SAF-100UG	100 ug	$499		Add to Cart

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