Mouse Anti-Rat GABA-A Receptor Alpha2 Monoclonal IgG1

Mfr.No.	SMC-486, SMC-486D, SMC-486D-A390, SMC-486D-A488, SMC-486D-A594, SMC-486D-ALP, SMC-486D-APC, SMC-486D-BI, SMC-486D-FITC, SMC-486D-HRP, SMC-486D-PCP, SMC-486D-RPE, SMC-486S
Immunogen Species	Rat
Alternative Names	GABA A receptor subunit alpha 2 Antibody, GABRA2 Antibody, Gamma aminobutyric acid A receptor Alpha 2 Antibody, GBRA2_Human Antibody
Categories	Antibodies
Cellular Localization	Cytoplasm
Certificate Of Analysis	A 1:100 dilution of SMC-486 was sufficient for detection of GABA-A R, Alpha2 in 20 ug of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Description	Mouse Anti-Rat GABA-A Receptor Alpha2 Monoclonal IgG1
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Fusion protein amino acids 350-385 (Cytoplasmic C-terminus) of rat GABA-A Receptor Alpha2, Rattus Norvegicus (Rat)
Immunogen Region	Fusion protein amino acids 350-385 (Cytoplasmic C-terminus) of rat GABA-A Receptor Alpha2
Isotype	IgG1
Launch Date	2015/03/10
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Rattus Norvegicus (Rat)
Species Reactivity Medium	Mouse, Rat, Human

Swissprot	P23576
Accession Number	NP_001129251.1
Gene Id	289606
Target	GABA A Receptor
Clone No	S399-19
Research Area	Neurotransmitter Receptors, GABA Receptors, GABAA Receptors, Neuroscience

Buffer	PBS pH7.4, 50% glycerol, 0.1% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification	Protein G Purified
Scientific Background	The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~55kDa. Does not cross-react with GABA-A Receptor Alpha1.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	IHC, WB, ICC/IF
Description	WB ; IHC ; ICC ; IF
Dilution	WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Bracamontes J.R. and Steinbach J.H. (2008) J Bio Chem. 283: 26128-26136. 2. Macdonald R.L., Olsen R.W. (1993) Annu Rev Neurosci. 17: 569-602.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11905103-1	SMC-486D	Unconjugated	100 ug	$330	Add to Cart
BHA11905103-2	SMC-486D-A390	ATTO 390	100 ug	$384	Add to Cart
BHA11905103-3	SMC-486D-A488	ATTO 488	100 ug	$383	Add to Cart
BHA11905103-4	SMC-486D-A594	ATTO 594	100 ug	$383	Add to Cart
BHA11905103-5	SMC-486D-ALP	Alkaline Phosphatase	100 ug	$376	Add to Cart
BHA11905103-6	SMC-486D-APC	APC	100 ug	$382	Add to Cart
BHA11905103-7	SMC-486D-BI	Biotin	100 ug	$378	Add to Cart
BHA11905103-8	SMC-486D-FITC	FITC	100 ug	$374	Add to Cart
BHA11905103-9	SMC-486D-HRP	HRP	100 ug	$370	Add to Cart
BHA11905103-10	SMC-486D-PCP	PerCP	100 ug	$382	Add to Cart
BHA11905103-11	SMC-486D-RPE	RPE	100 ug	$380	Add to Cart
BHA11905103-12	SMC-486S	Unconjugated	12 ug	$44	Add to Cart

GABA-A Receptor Alpha 2 Antibody, Clone S399-19 - SMC-486