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Home / Antibodies

FRS3 Antibody

SKU : BHA10558127

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA268108
Alternative Names	fibroblast growth factor receptor substrate 3; FRS2B; FRS2beta; MGC17167; SNT-2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.Xu H., J. Biol. Chem. 273:17987-17990(1998).Mungall A.J., Nature 425:805-811(2003).The MGC Project Team; Genome Res. 14:2121-2127(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human FRS3.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. Xu H., J. Biol. Chem. 273:17987-17990(1998). Mungall A.J., Nature 425:805-811(2003). The MGC Project Team; Genome Res. 14:2121-2127(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total FRS3 protein.
Subcellular Location	Membrane, Lipid-anchor

Uniprot	O43559
Database Links	HGNC:16970 OMIM:607744 KEGG:hsa:10817 STRING:9606.ENSP00000259748 UniGene:Hs.194208
Function	Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558127	CSB-PA268108	100ul	$297		Add to Cart

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