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Home / Primary Antibodies

Frataxin Antibody / FXN (V3997IHC)

SKU : BHA17125826

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NSJ Bioreagents

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Mfr.No.	V3997IHC-7ML
Clonality	Monoclonal (mouse origin)
Description	Reduced expression of frataxin is the cause of Friedreich's ataxia (FRDA), a lethal neurodegenerative disease. The reduction in frataxin gene expression may be attributable from either the silencing of transcription of the frataxin gene because of epigenetic modifications in the chromosomal entity or from the inability of splicing the expanded GAA repeats in the first intron of the pre-mRNA as seen in bacteria and human cells or both. The expansion of intronic trinucleotide repeat GAA results in Friedreich's ataxia. (Wiki)
Formulation	Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; For IHC use only
Host	Mouse
Immunogen Region	Amino acids 57-210 from the human protein were used as the immunogen for this Frataxin antibody.
Isotype	Mouse IgG2b, kappa
Species Reactivity	Human
Note	Optimal dilution of the Frataxin antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Uniprot	Q16595

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Frataxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125826	V3997IHC-7ML	7 ml	$499		Add to Cart

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