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Home / Antibodies

FOXP2 Antibody

SKU : BHA10557553

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA193153
Alternative Names	SPCH1; CAGH44; TNRC10
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Involved in neural mechanisms mediating the development of speech and language.Bruce H.A., Margolis R.L.Hum. Genet. 111:136-144(2002) Teramitsu I., Kudo L.C., London S.E., Geschwind D.H., White S.A.J. Neurosci. 24:3152-3163(2004)
Host	Rabbit
Immunogen	Peptide sequence around aa.707~711(E-E-P-L-S) derived from Human FOXP2.
Involvement In Disease	Speech-language disorder 1 (SPCH1)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Involved in neural mechanisms mediating the development of speech and language. Bruce H.A., Margolis R.L.Hum. Genet. 111:136-144(2002) Teramitsu I., Kudo L.C., London S.E., Geschwind D.H., White S.A.J. Neurosci. 24:3152-3163(2004)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of total FOXP2 protein.
Subcellular Location	Nucleus

Uniprot	O15409
Database Links	HGNC:13875 OMIM:602081 KEGG:hsa:93986 STRING:9606.ENSP00000386200 UniGene:Hs.282787
Function	Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
Tissue Specificity	Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung.

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557553	CSB-PA193153	100ul	$297		Add to Cart

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