Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell developmentHamdan F.F., Daoud H., Rochefort D., Piton A. J. Hum. Genet. 87:671-678(2010)
Host
Rabbit
Immunogen
Peptide sequence around aa. 669~673 (D-E-P-V-N
Involvement In Disease
Mental retardation with language impairment and autistic features (MRLIAF)
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development
Hamdan F.F., Daoud H., Rochefort D., Piton A. J. Hum. Genet. 87:671-678(2010)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous level of total FOXP1 protein.
Isoform 8 is specifically expressed in embryonic stem cells.
Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.