May play an important role in cell fate determination during lung development and in spermatogenesis. Li C.-S., Chae S.-C., Lee J.-H., Zhang Q., Chung H.-T.J. Hum. Genet. 51:292-297(2006)
Host
Rabbit
Immunogen
Peptide sequence around aa.413~417( D-W-A-S-V) derived from Human Foxj1 (HFH4).
Involvement In Disease
Allergic rhinitis (ALRH)
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
May play an important role in cell fate determination during lung development and in spermatogenesis.
Li C.-S., Chae S.-C., Lee J.-H., Zhang Q., Chung H.-T.J. Hum. Genet. 51:292-297(2006)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous level of total Foxj1 (HFH4) protein.
Transcription factor specifically required for the formation of motile cilia. Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157. Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T).
Protein Families
FOXJ1 family
Tissue Specificity
Testis, oviduct, lung and brain cortex.
Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.