The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
Recombinant full-length human FOXB1 protein was used as the immunogen for the FOXB1 antibody.
Isotype
Mouse IgG1
Species Reactivity
Human
Note
Optimal dilution of the FOXB1 antibody should be determined by the researcher.
Uniprot
Q99853
Format
Purified
Purity
Protein A/G affinity
Storage
Aliquot the FOXB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Applications
ELISA, FACS, IF
Description
ELISA (order BSA-free format for coating),Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml