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Home / Primary Antibodies

FOXA1 Antibody (V3371SAF)

SKU : BHA17125013

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NSJ Bioreagents

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Mfr.No.	V3371SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (a and beta), HNF-3 (a, beta and gamma), HNF-4 (a and gamma), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A human partial recombinant protein corresponding to amino acids 372-472 was used as the immunogen for this FOXA1 antibody.
Isotype	Mouse IgG2a, kappa
Species Reactivity	Human, Rat
Note	The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FOXA1 antibody to be titered up or down for optimal performance.

Uniprot	P55317

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the FOXA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB, IHC-P, FACS, IF
Description	Weste blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Immunofluorescence: 2-4ug/ml,Flow cytometry: 1-2ug/million cells

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125013	V3371SAF-100UG	100 ug	$499		Add to Cart

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