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Home / Primary Antibodies

FOLH1 Antibody

SKU : BHA10557651

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA167493
Alternative Names	FGCP; Folate hydrolase 1; FOLH; FOLH1; GCP2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4and isoform PSM-5would appear to be physiologically irrelevant. Involved in prostate tumor progression. Qin B et al. Identification of a LNCaP-specific binding peptide using phage display. Pharm Res 28:2422-34 (2011)
Host	Rabbit
Immunogen	Peptide sequence around aa.738~750 (A-A-E-T-L) derived Human from PSMA.
Reactivity	Human
Regulatory	RUO
Relevance	Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4and isoform PSM-5would appear to be physiologically irrelevant. Involved in prostate tumor progression. Qin B et al. Identification of a LNCaP-specific binding peptide using phage display. Pharm Res 28:2422-34 (2011)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of total PSMA protein.
Subcellular Location	Cell membrane, Single-pass type II membrane protein, SUBCELLULAR LOCATION: Isoform PSMA': Cytoplasm

Uniprot	Q04609
Database Links	HGNC:3788 OMIM:600934 KEGG:hsa:2346 STRING:9606.ENSP00000256999 UniGene:Hs.551896
Function	Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.; FUNCTION
Protein Families	Peptidase M28 family, M28B subfamily
Tissue Specificity	Highly expressed in prostate epithelium. Detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). Detected in the small intestine, brain, kid

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557651	CSB-PA167493	100ul	$297		Add to Cart

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