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Home / Antibodies

Filaggrin Antibody (V3840SAF)

SKU : BHA17125661

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NSJ Bioreagents

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Mfr.No.	V3840SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate coified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A portion of amino acids 998-1104 from the human protein were used as the immunogen for this Filaggrin antibody.
Isotype	Mouse IgG2b, kappa
Species Reactivity	Human
Note	Optimal dilution of the Filaggrin antibody should be determined by the researcher.

Uniprot	P20930

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Filaggrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125661	V3840SAF-100UG	100 ug	$499		Add to Cart

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