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Home / Antibodies

FHR-5 Antibody / Complement factor H-related protein 5 / CFHR5 (F54834)

SKU : BHA17103295

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NSJ Bioreagents

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Mfr.No.	F54834, F54834-0.08ML, F54834-0.4ML
Antigen	FHR-5
Clonality	Polyclonal
Description	CFHR5 / FHR-5 is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). (provided by RefSeq).
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 203-231 from the human protein was used as the immunogen for the FHR-5 antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	Q9BXR6

Format	Purified
Purification	Antigen affinity purified
Storage	Aliquot the FHR-5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	FACS, IHC-P, WB
Dilution	Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE): 1:5-1:100, Western blot: 1:500-1:1000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17103295-1	F54834-0.08ML	0.08ml	$165		Add to Cart
BHA17103295-2	F54834-0.4ML	0.4ml	$379		Add to Cart

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