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Home / Primary Antibodies

FGFR1 Antibody / Fibroblast growth factor receptor 1 (RQ5362)

SKU : BHA17110038

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NSJ Bioreagents

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Mfr.No.	RQ5362
Clonality	Monoclonal
Description	The protein encoded by the FGFR1 gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alteatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. (RefSeq)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human FGFR1 was used as the immunogen for the FGFR1 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P11362
Clone No	EHC-6

Format	Purified
Purification	Affinity purified
Storage	Store the FGFR1 antibody at -20°C.

Applications	WB
Dilution	Weste blot: 1:500-1:1000

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110038	RQ5362	100ul	$419		Add to Cart

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