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Home / Antibodies

FCGR2A Antibody

SKU : BHA10558886

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA985077
Alternative Names	Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.Stuart S.G., J. Exp. Med. 166:1668-1684(1987).Brooks D.G., J. Exp. Med. 170:1369-1385(1989).Gregory S.G., Nature 441:315-321(2006).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human FCGR2A.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. Stuart S.G., J. Exp. Med. 166:1668-1684(1987). Brooks D.G., J. Exp. Med. 170:1369-1385(1989). Gregory S.G., Nature 441:315-321(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total FCGR2A protein.
Subcellular Location	Cell membrane, Single-pass type I membrane protein

Uniprot	P12318
Database Links	HGNC:3616 OMIM:146790 KEGG:hsa:2212 STRING:9606.ENSP00000271450 UniGene:Hs.352642
Function	Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Pathway	Fc gamma R-mediated phagocytosis Osteoclast differentiation
Tissue Specificity	Found on monocytes, neutrophils and eosinophil platelets.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558886	CSB-PA985077	100ul	$297		Add to Cart

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