A member of the family of mammalian F-box proteins. F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 aminoacid motif, the F box (so named because cyclin F was one of the first proteins in which this motif was identified) . Some F-box proteins have been shown to be critical for the controlled degradation of cellular regulatory proteins.Hurtado del Pozo C,et al. (2010) Obesity (Silver Spring).18(5):897-903.Dubacq C, et al. (2002) Eukaryot Cell.1(4):568-82.Devoto A, et al.(2002) Plant J.32(4):457-66.
Host
Rabbit
Immunogen
Peptide sequence around aa.1~5 (M-S-L-L-A) derived from Fruit fly F box and leucine-rich-repeat gene 4.
Raised In
Rabbit
Reactivity
Drosophila melanogaster
Regulatory
RUO
Relevance
A member of the family of mammalian F-box proteins. F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 aminoacid motif, the F box (so named because cyclin F was one of the first proteins in which this motif was identified) . Some F-box proteins have been shown to be critical for the controlled degradation of cellular regulatory proteins.
Hurtado del Pozo C,et al. (2010) Obesity (Silver Spring).18(5):897-903. Dubacq C, et al. (2002) Eukaryot Cell.1(4):568-82. Devoto A, et al.(2002) Plant J.32(4):457-66.
Species
Drosophila Melanogaster (Fruit Fly)
Specificity
The antibody detects endogenous level of total F box and leucine-rich-repeat gene 4 protein.
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.