FAST kinase domain-containing protein 2; FASTKD2; KIAA0971;
Categories
Primary Antibodies
Clonality
polyclonal
Description
This gene encodes a protein that is localized in the mitochondrial inner compartment and that may play a role in mitochondrial apoptosis. Nonsense mutations have been reported to result in cytochrome c oxidase deficiency.Hu R.-M., Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).Hillier L.W., Nature 434:724-731(2005).Ota T., Nat. Genet. 36:40-45(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human FAKD2.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
This gene encodes a protein that is localized in the mitochondrial inner compartment and that may play a role in mitochondrial apoptosis. Nonsense mutations have been reported to result in cytochrome c oxidase deficiency.
Hu R.-M., Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000). Hillier L.W., Nature 434:724-731(2005). Ota T., Nat. Genet. 36:40-45(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total FAKD2 protein.
Plays an important role in assembly of the mitochondrial large ribosomal subunit
Protein Families
FAST kinase family
Tissue Specificity
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle and thyroid.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.