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Home / Primary Antibodies

FARP2 Antibody

SKU : BHA10557781

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA977826
Alternative Names	FERM; RhoGEF and pleckstrin domain protein 2; FGD1-related Cdc42-GEF; FIR; FRG
Categories	Primary Antibodies
Clonality	polyclonal
Description	Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion By similarity.Nagase T., DNA Res. 5:31-39(1998).The MGC Project Team, Genome Res. 14:2121-2127(2004).Jandrig B., Oncogene 23:9295-9302(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human FIR.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion By similarity. Nagase T., DNA Res. 5:31-39(1998). The MGC Project Team, Genome Res. 14:2121-2127(2004). Jandrig B., Oncogene 23:9295-9302(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total FIR protein.

Uniprot	O94887
Database Links	HGNC:16460 OMIM:617586 KEGG:hsa:9855 STRING:9606.ENSP00000264042 UniGene:Hs.726316
Function	Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity).
Pathway	Adherens junction Rap1 signaling pathway

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557781	CSB-PA977826	100ul	$297		Add to Cart

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