Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Host
Rabbit
Immunogen Region
A portion of amino acids 60-94 from human Factor XIIIa was used as the immunogen for the Factor XIIIa antibody.
Isotype
Ig
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Uniprot
P00488
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
Aliquot the Factor XIIIa antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.