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Home / Primary Antibodies

F2R Antibody

SKU : BHA10557738

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA212441
Alternative Names	CF2R; Coagulation factor II receptor; F2R; PAR-1; Proteinase activated receptor 1 precursor
Categories	Primary Antibodies
Clonality	polyclonal
Description	High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.Vu T.-K.H., Cell 64:1057-1068(1991).Kahn M.L., J. Clin. Invest. 103:879-887(1999).Cargill M., Nat. Genet. 22:231-238(1999).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human Thrombin Receptor.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development. Vu T.-K.H., Cell 64:1057-1068(1991). Kahn M.L., J. Clin. Invest. 103:879-887(1999). Cargill M., Nat. Genet. 22:231-238(1999).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total Thrombin Receptor protein.
Subcellular Location	Cell membrane, Multi-pass membrane protein

Uniprot	P25116
Database Links	HGNC:3537 OMIM:187930 KEGG:hsa:2149 STRING:9606.ENSP00000321326 UniGene:Hs.482562
Function	High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
Pathway	Calcium signaling pathway cAMP signaling pathway PI3K-Akt signaling pathway Regulation of actin cytoskeleton Complement and coagulation cascades Oxidative Phosphorylation Phospholipase D signaling pathway Rap1 signaling pathway
Protein Families	G-protein coupled receptor 1 family
Tissue Specificity	Platelets and vascular endothelial cells.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557738	CSB-PA212441	100ul	$297		Add to Cart

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