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Home / Primary Antibodies

Ezrin Antibody / EZR (V8158SAF)

SKU : BHA17127272

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NSJ Bioreagents

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Mfr.No.	V8158SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Ezrin, Moesin and Radixin belong to a family of highly homologous Actinassociated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70% homology with Ezrin and are coexpressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific patte of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A recombinant human full-length protein was used as the immunogen for this Ezrin antibody.
Isotype	Mouse IgG2b, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P15311

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Ezrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB, IHC-P
Description	Weste blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/ezrin-antibody-spm244-v8158" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127272	V8158SAF-100UG	100 ug	$499		Add to Cart

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