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Home / Primary Antibodies

Exportin 2 antibody / CSE1L (F54382)

SKU : BHA17102855

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NSJ Bioreagents

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Mfr.No.	F54382, F54382-0.08ML, F54382-0.4ML
Clonality	Polyclonal
Description	Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be retued to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 55-84 from the human protein was used as the immunogen for the Exportin 2 antibody.
Isotype	Ig
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No
Subcellular Location	Nuclear, cytoplasmic

Uniprot	P55060

Format	Purified
Purification	SAS precipitation
Storage	Aliquot the Exportin 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	IHC-P, IF, WB
Dilution	Immunohistochemistry (FFPE): 1:25,Immunofluorescence: 1:25,Weste blot: 1:500-1:2000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17102855-1	F54382-0.08ML	0.08ml	$165		Add to Cart
BHA17102855-2	F54382-0.4ML	0.4ml	$389		Add to Cart

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