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Home / Primary Antibodies

Estrogen Receptor Antibody (alpha) (R31605)

SKU : BHA17104985

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NSJ Bioreagents

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Mfr.No.	R31605
Clonality	Polyclonal
Description	Estrogen receptor alpha (ER<font face=symbol>a</font>), also known as NR3A1, is one of two main types of estrogen receptor, a nuclear protein that is activated by the sex hormone estrogen. ERs are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. In humans, ER<font face=symbol>a</font> is encoded by the gene ESR1. It is mapped to 6q25.1. This gene is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2/beta. Estrogen and its receptors are essential for sexual development and reproductive function, it also play a role in other tissues such as bone.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human ERa partial recombinant protein (AA 425-595) was used as the immunogen for this Estrogen Receptor antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Nuclear

Gene Id	2099

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Estrogen Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P
Dilution	Weste blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104985	R31605	100 ug	$419		Add to Cart

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