This mAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
A portion of amino acids 290-560 was used as the immunogen for the Estrogen Receptor alpha antibody. The epitope of this mAb is between amino acids 300-550.
Isotype
Mouse IgG2a, kappa
Species Reactivity
Human
Note
Optimal dilution of the Estrogen Receptor alpha antibody should be determined by the researcher.
Uniprot
P03372
Format
Purified
Purity
Protein A/G affinity
Storage
Aliquot the Estrogen Receptor alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.