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Home / Antibodies

Estrogen Receptor alpha Antibody (V7060SAF)

SKU : BHA17125926

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NSJ Bioreagents

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Mfr.No.	V7060SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Estrogen receptor (ER) is an important regulator of growth and differentiation in the mammary gland. It is found in two forms, alpha and beta. Both forms are widely expressed, however, alpha is the predominant form in endometrium and breast cancer cells, and beta is more highly expressed in brain, kidney, heart, lung and bone. Activated Estrogen receptor dimerizes and forms both homo- and heterodimers. ER contains five domains: A-F. The A and B domain are able to weakly activate ER in the absence of ligand. The C domain binds DNA and the E domain contains the ligand binding site. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This antibody is specific to estrogen receptor alpha and shows minimal cross-reaction with other members of the family.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Estrogen Receptor alpha protein (aa 2-185) was used as the immunogen for this antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Titration of the Estrogen Receptor antibody may be required for optimal performance.

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Estrogen Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB
Description	Weste blot: 1-2ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125926	V7060SAF-100UG	100 ug	$499		Add to Cart

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