This mAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
Full length human protein was used as the immunogen for this Estrogen Receptor alpha antibody.
Isotype
Mouse IgG2a, kappa
Species Reactivity
Human
Note
The optimal dilution of the Estrogen Receptor alpha antibody for each application should be determined by the researcher.
Uniprot
P03372
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the Estrogen Receptor alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Applications
WB, IHC-P
Description
Weste blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT