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Home / Primary Antibodies

ERK1/2 (phospho Tyr222/205) Polyclonal Antibody

SKU : BHA13715181

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABP0049
Background	MAPK1 encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this MAPK1
Clonality	Polyclonal
Formulation	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Host	Rabbit
Immunogen	Synthesized peptide derived from human ERK1/2 around the phosphorylation site of Y222/205
Isotype	Rabbit IgG
Reactivity	Human, Mouse, Rat

Gene Id	5594/5595

Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide

Applications	Protein General Reagents

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715181	ABP0049	100ul	$229		Add to Cart

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