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Home / Antibodies

ERCC1 Antibody (RQ5198)

SKU : BHA17109914

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NSJ Bioreagents

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Mfr.No.	RQ5198
Clonality	Monoclonal
Description	The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. (RefSeq)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human ERCC1 was used as the immunogen for the ERCC1 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P07992
Clone No	AOFA-5

Format	Purified
Purification	Affinity purified
Storage	Store the ERCC1 antibody at -20°C.

Applications	WB
Dilution	Weste blot: 1:500-1:2000

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17109914	RQ5198	100ul	$419		Add to Cart

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