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Home / Primary Antibodies / IHC Antibodies

ER780 Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1]

SKU : BHA10327371

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1112US
Background	CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-2CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is eessed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.40 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 is one of the best negative selection markers for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources. s.
Categories	Primary Antibodies;Primary Antibodies///Flow Cytomerty(FACS)
Clonality	Monoclonal
Host	Rat
Isotype	Rat IgM, k
Reactivity	Mouse
Synonyms	B220,CD45,GP180,LCA,T200

Swissprot	P06800,P08575
Accession Number	19264,5788
Gene Id	19264, 5788
Clone No	RA3.3A 1/6.1

Buffer	PBS with 0.05% Proclin300, 1% BSA
Concentration	0.2 mg/mL
Storage	Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Applications	FCM

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SKU	Supplier No.	Size	Your price	Quantity
BHA10327371	E-AB-F1112US	25ug	$70		Add to Cart
BHA10327371	E-AB-F1112US	50ug	$120		Add to Cart
BHA10327371	E-AB-F1112US	100ug	$160		Add to Cart
BHA10327371	E-AB-F1112US	200ug	$250		Add to Cart

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