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Home / Primary Antibodies

EPOR (Ab-426) Antibody

BHA10557719
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
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Ask Merchant
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Sample Request
Uniprot P19235
Database Links

HGNC:3416

OMIM:133100

KEGG:hsa:2057

STRING:9606.ENSP00000222139

UniGene:Hs.631624

,

HGNC:3416

OMIM:133100

KEGG:hsa:2057

STRING:9606.ENSP00000222139

UniGene:Hs.631624
Function Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.; FUNCTION, Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.; FUNCTION
Pathway Jak-STAT signaling pathway PI3K-Akt signaling pathway Hematopoietic cell lineage, Jak-STAT signaling pathway PI3K-Akt signaling pathway Hematopoietic cell lineage
Protein Families Type I cytokine receptor family, Type 1 subfamily
Tissue Specificity Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow. Isoform EP
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format liquid, liquid
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Applications ELISA, WB
Description ELISA ; WB, WB ; ELISA, WB ; ELISA
Dilution

WB1:500-1:3000
Tested Application ELISA,WB;WB:1:500-1:3000, ELISA,WB;WB:1:500-1:3000
Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Western Blotting(WB) Protocol
SKU Supplier No. Size Your price Quantity
BHA10557719 CSB-PA826447 100ul $297
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