This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 59-86 from the human protein was used as the immunogen for this EpCAM antibody.
Isotype
Mouse IgG1
Species Reactivity
Human
Note
Titration of the EpCAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
P16422
Format
Ascites
Purity
Ascites
Storage
Aliquot the EpCAM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.