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Home / Primary Antibodies

EPCAM Antibody

SKU : BHA10557808

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA787369
Alternative Names	Tumor-associated calcium signal transducer 1 [Precursor]; Major gastrointestinal tumor-associated protein GA733-2; Epithelial cell surface antigen; Epithelial glycoprotein; EGP
Categories	Primary Antibodies
Clonality	polyclonal
Description	May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.Stad J., Cancer Res. 49:314-317(1989).Simon B., Proc. Natl. Acad. Sci. U.S.A. 87:2755-2759(1990).Perez M.S., J. Immunol. 142:3662-3667(1989).
Host	Rabbit
Immunogen	Synthesized peptide derived from inteal of Human TACD1.
Involvement In Disease	Diarrhea 5, with tufting enteropathy, congenital (DIAR5); Hereditary non-polyposis colorectal cancer 8 (HNPCC8)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. Stad J., Cancer Res. 49:314-317(1989). Simon B., Proc. Natl. Acad. Sci. U.S.A. 87:2755-2759(1990). Perez M.S., J. Immunol. 142:3662-3667(1989).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total TACD1 protein.
Subcellular Location	Lateral cell membrane, Single-pass type I membrane protein, Cell junction, tight junction

Uniprot	P16422
Database Links	HGNC:11529 OMIM:185535 KEGG:hsa:4072 STRING:9606.ENSP00000263735 UniGene:Hs.542050
Function	May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Protein Families	EPCAM family
Tissue Specificity	Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557808	CSB-PA787369	100ul	$297		Add to Cart

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