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Home / Primary Antibodies

ELOVL1 Antibody

SKU : BHA10558397

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA262320
Alternative Names	Elongation of very long chain fatty acids protein 1; ELOVL1; SSC1; CGI-88;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids (VLCFAs). Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.Asadi A., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.Lai C.-H., Genome Res. 10:703-713(2000).Ota T., Nat. Genet. 36:40-45(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human ELOVL1.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids (VLCFAs). Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs. Asadi A., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases. Lai C.-H., Genome Res. 10:703-713(2000). Ota T., Nat. Genet. 36:40-45(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ELOVL1 protein.
Subcellular Location	Endoplasmic reticulum membrane, Multi-pass membrane protein

Uniprot	Q9BW60
Database Links	HGNC:14418 OMIM:611813 KEGG:hsa:64834 STRING:9606.ENSP00000361536 UniGene:Hs.25597
Function	Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22
Protein Families	ELO family, ELOVL1 subfamily
Tissue Specificity	Ubiquitous.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558397	CSB-PA262320	100ul	$297		Add to Cart

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