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Home / Antibodies

EIF3K Antibody

SKU : BHA10558404

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA693741
Alternative Names	Eukaryotic translation initiation factor 3 subunit K;eIF3k;Eukaryotic translation initiation factor 3 subunit 12; eIF-3 p25; eIF-3 p28; eIF3k; Muscle-specific gene M9 protein;EIF3K;EIF3S12
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. HAMAP-Rule MF_03010Mayeur G.L., Eur. J. Biochem. 270:4133-4139(2003).Nawa G., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.Ye M., Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human EIF3K.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. HAMAP-Rule MF_03010Mayeur G.L., Eur. J. Biochem. 270:4133-4139(2003).Nawa G., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.Ye M., Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total EIF3K protein.
Subcellular Location	Nucleus, Cytoplasm

Uniprot	Q9UBQ5
Database Links	HGNC:24656 OMIM:609596 KEGG:hsa:27335 STRING:9606.ENSP00000248342 UniGene:Hs.314359
Function	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis
Protein Families	EIF-3 subunit K family
Tissue Specificity	Ubiquitous, with the highest levels of expression in brain, testis and kidney.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558404	CSB-PA693741	100ul	$297		Add to Cart

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