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Home / Antibodies

EGR1/EGR2 Antibody

SKU : BHA10557817

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA253458
Alternative Names	AT225; EGR-1; Early growth response protein 1; KROX-24; Krox-24 protein
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.Suggs S.V., Nucleic Acids Res. 18:4283-4283(1990).Shimizu N., J. Biochem. 111:272-277(1992).Wright J.J., Science 248:588-591(1990).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human EGR1/2.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. Suggs S.V., Nucleic Acids Res. 18:4283-4283(1990). Shimizu N., J. Biochem. 111:272-277(1992). Wright J.J., Science 248:588-591(1990).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total EGR1/2 protein.
Subcellular Location	Nucleus, Cytoplasm

Uniprot	P18146
Database Links	HGNC:3238 OMIM:128990 KEGG:hsa:1958 STRING:9606.ENSP00000239938 UniGene:Hs.326035
Function	Transcriptional regulator
Pathway	AGE-RAGE signaling pathway in diabetic complications Apelin signaling pathway
Protein Families	EGR C2H2-type zinc-finger protein family
Tissue Specificity	Detected in neutrophils (at protein level).

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557817	CSB-PA253458	100ul	$297		Add to Cart

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