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Home / Antibodies

EDC4 Antibody (RQ6550)

SKU : BHA17122811

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NSJ Bioreagents

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Mfr.No.	RQ6550
Clonality	Polyclonal (rabbit origin)
Description	Enhancer of mRNA-decapping protein 4 is a protein that in humans is encoded by the EDC4 gene. Enhancer of mRNA decapping 4 (EDC4) was originally identified as the autoantigen Ge-1 from a Sjogren's syndrome patient later diagnosed with primary biliary cirrhosis. EDC4 (also known as HEDLS) was later identified as an essential component of cytoplasmic P-bodies responsible for mRNA decapping and degradation. Identified EDC4 protein is found as a pair of isoforms generated by alteative splicing and contains several WD domains and a putative nuclear localization signal. EDC4 co-localizes with other P-body decapping proteins such as DCP1A, DCP2 and GW182. Experimental evidence suggests that EDC4 may be involved in miRNA-mediated translation repression.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An E. coli-derived human protein (amino acids K1082-L1388) was used as the immunogen for the EDC4 antibody.
Isotype	Rabbit IgG
Species Reactivity	Human
Note	Optimal dilution of the EDC4 antibody should be determined by the researcher.

Uniprot	Q6P2E9

Format	Antigen affinity purified
Purity	Affinity purified
Storage	After reconstitution, the EDC4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, FACS, Direct ELISA
Description	Weste blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122811	RQ6550	100ug	$419		Add to Cart

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