Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. (UniProt)
Formulation
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Host
Mouse
Isotype
Mouse IgG1
Species Reactivity
Human, Mouse
Note
The stated application concentrations are suggested starting points. Titration of the E-Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity.