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Home / Antibodies

E-Cadherin Antibody / CDH1 (RQ5389)

SKU : BHA17110062

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NSJ Bioreagents

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Mfr.No.	RQ5389
Antigen	E-Cadherin
Clonality	Monoclonal
Description	The CDH1 gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. (RefSeq)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human E-Cadherin / CDH1 was used as the immunogen for the E-Cadherin antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No
Subcellular Location	Cytoplasmic, plasma membrane

Uniprot	P12830
Clone No	COH-3

Format	Purified
Purification	Affinity purified
Storage	Store the E-Cadherin antibody at -20°C.

Applications	IHC-P, WB
Dilution	Western blot: 1:1000-1:5000,Immunohistochemistry (FFPE): 1:50-1:200

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110062	RQ5389	100 ul	$419		Add to Cart

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