Rabbit Anti-Human DUSP3 Polyclonal

Mfr.No.	SPC-1124, SPC-1124D, SPC-1124D-A390, SPC-1124D-A488, SPC-1124D-A594, SPC-1124D-BI, SPC-1124D-FITC
Immunogen Species	Human
Alternative Names	Dual specificity phosphatase 3 antibody, Dual specificity protein phosphatase 3 antibody, Dual specificity protein phosphatase VHR antibody, DUS3_HUMAN antibody, DUSP3 antibody, Serine/threonine specific protein phosphatase antibody, Vaccinia H1-related phosphatase antibody, Vaccinia virus phosphatase VH1 related antibody, VHR antibody
Categories	Antibodies
Cellular Localization	Nucleus
Certificate Of Analysis	A 1:250 dilution of SPC-1124 was sufficient for detection of DUSP3 in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human DUSP3 Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A synthetic peptide corresponding to the C-terminal of human DUSP3 (AA 171-185), Homo Sapiens (Human)
Immunogen Region	A synthetic peptide corresponding to the C-terminal of human DUSP3 (AA 171-185)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Human

Swissprot	P51452
Accession Number	NP_004081
Gene Id	1845
Target	DUSP3
Research Area	Tyrosine Phosphatases\| Cell Signaling, Cell Signaling, Metabolism, Amino Acid Metabolism, Protein Phosphorylation, Serine / Threonine Kinases, Cancer

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Scientific Background	DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 20.478 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11915048-1	SPC-1124D	Unconjugated	100 ul	$331	Add to Cart
BHA11915048-2	SPC-1124D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11915048-3	SPC-1124D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11915048-4	SPC-1124D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11915048-5	SPC-1124D-BI	Biotin	100 ul	$380	Add to Cart
BHA11915048-6	SPC-1124D-FITC	FITC	100 ul	$375	Add to Cart

DUSP3 Antibody - SPC-1124