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Home / Primary Antibodies

DKK2 Antibody / Dickkopf-2 (F54702)

SKU : BHA17103166

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NSJ Bioreagents

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Mfr.No.	F54702, F54702-0.08ML, F54702-0.4ML
Clonality	Polyclonal
Description	The 259-amino acid DKK2 protein, like DKK1, DKK3, and DKK4, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cys residues each. The second cys region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northe blot analysis revealed expression of 4.0- and 4.5-kb DKK2 transcripts in heart, brain, skeletal muscle, and lung. Weste blot analysis showed that DKK2 is secreted as a 15- to 17-kD protein. Functional analysis determined that DKK2 does not block Xenopus Wnt8 induction of a secondary axis in frog embryos.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 31-62 from the human protein was used as the immunogen for the Dickkopf-2 antibody.
Isotype	Ig
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No

Uniprot	Q9UBU2

Format	Purified
Purification	Purified
Storage	Aliquot the Dickkopf-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	IHC-P, WB
Dilution	Immunohistochemistry (FFPE): 1:25, Weste blot: 1:500-1:2000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17103166-1	F54702-0.08ML	0.08ml	$165		Add to Cart
BHA17103166-2	F54702-0.4ML	0.4ml	$379		Add to Cart

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