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Home / Antibodies

Dicer Antibody (R30146)

SKU : BHA17103936

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Mfr.No.	R30146
Clonality	Polyclonal
Description	Dicer is an enzyme that in humans is encoded by the DICER1 gene. It is mapped to 14q32.13. The gene, a member of the ribonuclease III (RNaseIII) family, is involved in the generation of microRNAs (miRNAs), which modulate gene expression at the posttranscriptional level. The enzyme possesses an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. It is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. In addition, it is required for formation of the RNA induced silencing complex (RISC). Dicer also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 1-195) was used as the immunogen for this Dicer antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Gene Id	23405

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Dicer antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, IF, ICC, FACS
Dilution	Weste blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunofluorescence: 2-4ug/ml,Flow cytometry: 1-3ug/million cells

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17103936	R30146	100 ug	$419		Add to Cart

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