This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alteative splicing results in multiple transcript variants.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
A portion of amino acids 879-908 from the human protein was used as the immunogen for this Dicer antibody.
Isotype
Mouse IgG1
Species Reactivity
Human
Note
Titration of the Dicer antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
Q9UPY3
Format
Ascites
Purity
Ascites
Storage
Aliquot the Dicer antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.