Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition.Tang W., J. Biol. Chem. 271:10237-10241(1996).Tang W., Gene 239:185-192(1999).Sjoeblom T., Science 314:268-274(2006).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human DGKE.
Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition.
Tang W., J. Biol. Chem. 271:10237-10241(1996). Tang W., Gene 239:185-192(1999). Sjoeblom T., Science 314:268-274(2006).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total DGKE protein.
Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition.
Pathway
Oxidative Phosphorylation Phosphatidylinositol signaling system Phospholipase D signaling pathway
Protein Families
Eukaryotic diacylglycerol kinase family
Tissue Specificity
Expressed predominantly in testis. Expressed in endothelium, platelets and podocytes (at protein level).
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.