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Home / Antibodies

DDR2 Antibody (F53649)

SKU : BHA17119825

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NSJ Bioreagents

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Mfr.No.	F53649-0.1ML
Clonality	Monoclonal (mouse origin)
Description	Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alteative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. (provided by RefSeq).
Formulation	In ascites with 0.09% sodium azide
Host	Mouse
Immunogen Region	A portion of amino acids 290-320 from the human protein was used as the immunogen for this DDR2 antibody.
Isotype	Mouse IgG1
Species Reactivity	Human
Note	Titration of the DDR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	Q16832

Format	Ascites
Purity	Ascites
Storage	Aliquot the DDR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Description	Weste blot: 1:100-1:1600

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119825	F53649-0.1ML	0.1 ml	$379		Add to Cart

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