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Home / Primary Antibodies

DCTN2 Antibody

SKU : BHA10559204

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA193732
Alternative Names	50 kDa dynein-associated polypeptide; DCT2; DCTN-50; DCTN2; dynactin complex 50 kDa subunit
Categories	Primary Antibodies
Clonality	polyclonal
Description	Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.Scott S. Grieshaber, J. Cell Sci., Sep 2003; 116: 3793. Janis K. Burkhardt, J. Cell Biol., Oct 1997; 139: 469. Karin A. Melkonian, J. Biol. Chem., Apr 2007; 10.1074.Lili Yue, J. Biol. Chem., Jul 2000; 275: 23948.
Host	Rabbit
Immunogen	Synthesized peptide derived from Human p50 dynamitin.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development. Scott S. Grieshaber, J. Cell Sci., Sep 2003; 116: 3793. Janis K. Burkhardt, J. Cell Biol., Oct 1997; 139: 469. Karin A. Melkonian, J. Biol. Chem., Apr 2007; 10.1074. Lili Yue, J. Biol. Chem., Jul 2000; 275: 23948.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total p50 dynamitin protein.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Membrane, Peripheral membrane protein

Uniprot	Q13561
Database Links	HGNC:2712 OMIM:607376 KEGG:hsa:10540 STRING:9606.ENSP00000408910 UniGene:Hs.289123
Function	Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
Protein Families	Dynactin subunit 2 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559204	CSB-PA193732	100ul	$297		Add to Cart

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