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Home / Antibodies

DC-SIGN Antibody / CD209 (V7418)

SKU : BHA17116191

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NSJ Bioreagents

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Mfr.No.	V7418, V7418-20UG, V7418-100UG
Antigen	DC-SIGN
Clonality	Monoclonal
Description	DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Rabbit
Immunogen Region	Recombinant human protein was used as the immunogen for the DC-SIGN antibody.
Isotype	IgG,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	Yes
Subcellular Location	Plasma membrane, secreted

Uniprot	Q9NNX6
Clone No	C209/2749R

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein A affinity chromatography
Storage	Store the DC-SIGN antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	IHC-P
Dilution	Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17116191-1	V7418-20UG	20ug	$219		Add to Cart
BHA17116191-2	V7418-100UG	100ug	$499		Add to Cart

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