Cytokeratin 5/Keratin 5/KRT5 is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelial, and mesothelium. Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Rabbit
Immunogen Region
A portion of amino acids 316-590 was used as the immunogen for the recombinant Keratin 5 antibody.
Isotype
Rabbit IgG
Species Reactivity
Human
Note
Optimal dilution of the recombinant Keratin 5 antibody should be determined by the researcher.
Uniprot
P13647
Format
Purified
Purity
Protein A/G affinity
Storage
Aliquot the recombinant Keratin 5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.