This MAb recognizes an intermediate filament protein of 46kDa, identified as cytokeratin 20 (KRT20). KRT20 is abundantly expressed in goblet cells and enterocytes of the gastrointestinal tract. It is a useful marker of pancreatic and colorectal cancer. KRT20 is expressed under normal, hyperplastic and neoplastic conditions. It has been detected in adenocarcinomas of the colon, stomach and biliary tract. Breast carcinomas are generally non-reactive.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Rabbit
Immunogen Region
A portion of amino acids 196-323 was used as the immunogen for the recombinant Keratin 20 antibody.
Isotype
Rabbit IgG, kappa
Species Reactivity
Human
Note
Optimal dilution of the recombinant Keratin 20 antibody should be determined by the researcher.
Uniprot
P35900
Format
Purified
Purity
Protein A/G affinity
Storage
Aliquot the recombinant Keratin 20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.