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Home / Antibodies

CYP2D6 Antibody

SKU : BHA10558122

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA263930
Alternative Names	Cytochrome P450 2D6; EC 1.14.14.1; CYPIID6; P450-DB1; Debrisoquine 4-hydroxylase
Categories	Primary Antibodies
Clonality	polyclonal
Description	Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.Tyndale R., Pharmacogenetics 1:26-32(1991).Yokota H., Pharmacogenetics 3:256-263(1993).Evert B., Naunyn Schmiedebergs Arch. Pharmacol. 350:434-439(1994).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human Cytochrome P450 2D6.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. Tyndale R., Pharmacogenetics 1:26-32(1991). Yokota H., Pharmacogenetics 3:256-263(1993). Evert B., Naunyn Schmiedebergs Arch. Pharmacol. 350:434-439(1994).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total Cytochrome P450 2D6 protein.
Subcellular Location	Endoplasmic reticulum membrane, Peripheral membrane protein, Microsome membrane, Peripheral membrane protein

Uniprot	P10635
Database Links	HGNC:2625 OMIM:124030 KEGG:hsa:1565 STRING:9606.ENSP00000353820 UniGene:Hs.648256
Function	Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
Protein Families	Cytochrome P450 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558122	CSB-PA263930	100ul	$297		Add to Cart

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