Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.Romkes M., Biochemistry 30:3247-3255(1991).de Morais S.M., Biochem. Biophys. Res. Commun. 194:194-201(1993).Deloukas P., Nature 429:375-381(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human Cytochrome P450 2C8/9/18/19.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Romkes M., Biochemistry 30:3247-3255(1991). de Morais S.M., Biochem. Biophys. Res. Commun. 194:194-201(1993). Deloukas P., Nature 429:375-381(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Cytochrome P450 2C8/9/18/19 protein.
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Protein Families
Cytochrome P450 family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.