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Home / Antibodies

CYP2A6 Antibody

SKU : BHA10558356

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA909765
Alternative Names	Cytochrome P450 2A6; EC 1.14.14.1; CYPIIA6; Coumarin 7-hydroxylase; P450 IIA3
Categories	Primary Antibodies
Clonality	polyclonal
Description	Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.Miles J.S., ic Acids Res. 17:2907-2917(1989).Yamano S., Biochemistry 29:1322-1329(1990).Saito S., J. Hum. Genet. 48:249-270(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human Cytochrome P450 2A6.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity. Miles J.S., ic Acids Res. 17:2907-2917(1989). Yamano S., Biochemistry 29:1322-1329(1990). Saito S., J. Hum. Genet. 48:249-270(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total Cytochrome P450 2A6 protein.
Subcellular Location	Endoplasmic reticulum membrane, Peripheral membrane protein, Microsome membrane, Peripheral membrane protein

Uniprot	P11509
Database Links	HGNC:2610 OMIM:122720 KEGG:hsa:1548 STRING:9606.ENSP00000301141 UniGene:Hs.250615
Function	Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.
Protein Families	Cytochrome P450 family
Tissue Specificity	Liver.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558356	CSB-PA909765	100ul	$297		Add to Cart

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